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In prehistoric times, knowledge and technique were passed from generation to generation in an oral tradition. For instance, the domestication of maize for agriculture has been dated to about 9,000 years ago in southern Mexico, before the development of writing systems. Similarly, archaeological evidence indicates the development of astronomical knowledge in preliterate societies. The oral tradition of preliterate societies had several features, the first of which was its fluidity. New information was constantly absorbed and adjusted to new circumstances or community needs. There were no archives or reports. This fluidity was closely related to the practical need to explain and justify a present state of affairs. Another feature was the tendency to describe the universe as just sky and earth, with a potential underworld. They were also prone to identify causes with beginnings, thereby providing a historical origin with an explanation. There was also a reliance on a "medicine man" or "wise woman" for healing, knowledge of divine or demonic causes of diseases, and in more extreme cases, for rituals such as exorcism, divination, songs, and incantations. Finally, there was an inclination to unquestioningly accept explanations that might be deemed implausible in more modern times while at the same time not being aware that such credulous behaviors could have posed problems. The development of writing enabled humans to store and communicate knowledge across generations with much greater accuracy. Its invention was a prerequisite for the development of philosophy and later science in ancient times. Moreover, the extent to which philosophy and science would flourish in ancient times depended on the efficiency of a writing system (e.g., use of alphabets).

== Ancient Near East and North East Africa ==

The earliest roots of science can be traced to the Ancient Near East and North East Africa c.30001200 BCE in particular to Ancient Egypt and Mesopotamia.

=== Ancient Egypt ===

Archaeological evidence has suggested that the Ancient Egyptian counting system had origins in Sub-Saharan Africa. Also, fractal geometry designs which are widespread among Sub-Saharan African cultures are also found in Egyptian architecture and cosmological signs.The Ishango bone, according to scholar Alexander Marshack, may have influenced the later development of mathematics in Egypt as, like some entries on the Ishango bone, Egyptian arithmetic also made use of multiplication by 2; this however, is disputed. Megalithic structures located in Nabta Playa, Upper Egypt featured astronomy, calendar arrangements in alignment with the heliacal rising of Sirius and supported calibration the yearly calendar for the annual Nile flood. These practices have been linked with the emergence of cosmology in Old Kingdom Egypt.

==== Number system and geometry ==== Starting c.3000 BCE, the ancient Egyptians developed a numbering system that was decimal in character and had oriented their knowledge of geometry to solving practical problems such as those of surveyors and builders. Their development of geometry was itself a necessary development of surveying to preserve the layout and ownership of farmland, which was flooded annually by the Nile. The 3-4-5 right triangle and other rules of geometry were used to build rectilinear structures, and the post and lintel architecture of Egypt.

==== Disease and healing ====

Egypt was also a center of alchemy research for much of the Mediterranean. According to the medical papyri (written c.25001200 BCE), the ancient Egyptians believed that disease was mainly caused by the invasion of bodies by evil forces or spirits. Thus, in addition to medicine, therapies included prayer, incantation, and ritual. The Ebers Papyrus, written c.1600 BCE, contains medical recipes for treating diseases related to the eyes, mouth, skin, internal organs, and extremities, as well as abscesses, wounds, burns, ulcers, swollen glands, tumors, headaches, and bad breath. The Edwin Smith Papyrus, written at about the same time, contains a surgical manual for treating wounds, fractures, and dislocations. The Egyptians believed that the effectiveness of their medicines depended on the preparation and administration under appropriate rituals. Medical historians believe that ancient Egyptian pharmacology, for example, was largely ineffective. Both the Ebers and Edwin Smith papyri applied the following components to the treatment of disease: examination, diagnosis, treatment, and prognosis, which display strong parallels to the basic empirical method of science and, according to G. E. R. Lloyd, played a significant role in the development of this methodology.

==== Calendar ==== The ancient Egyptians even developed an official calendar that contained twelve months, thirty days each, and five days at the end of the year. Unlike the Babylonian calendar or the ones used in Greek city-states at the time, the official Egyptian calendar was much simpler as it was fixed and did not take lunar and solar cycles into consideration.

=== Ancient Nubia ===

==== Medicine ==== Nubian mummies studied in the 1990s revealed that Kush was a pioneer of early antibiotics. Tetracycline was being used by Nubians, based on bone remains between 350 AD and 550 AD. The antibiotic was in wide commercial use only in the mid 20th century. The theory states that earthen jars containing grain used for making beer contained the bacterium streptomyces, which produced tetracycline. Although Nubians were not aware of tetracycline, they could have noticed that people fared better by drinking beer than just consuming the grain itself. According to Charlie Bamforth, a professor of biochemistry and brewing science at the University of California, Davis, "They must have consumed it because it was rather tastier than the grain from which it was derived."

=== Mathematics === Based on engraved plans of Meroitic King Amanikhabali's pyramids, Nubians had a sophisticated understanding of mathematics as they appreciated the harmonic ratio. The engraved plans are indicative of much to be revealed about Nubian mathematics. The ancient Nubians also established a system of geometry which they used in creating early versions of sun clocks. During the Meroitic period in Nubian history, the Nubians used a trigonometric methodology similar to the Egyptians.

=== Mesopotamia ===