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| title | chunk | source | category | tags | date_saved | instance |
|---|---|---|---|---|---|---|
| World Community Grid | 6/7 | https://en.wikipedia.org/wiki/World_Community_Grid | reference | science, encyclopedia | 2026-05-05T02:59:12.872858+00:00 | kb-cron |
World Community Grid and researchers supported by Decrypthon, a partnership between AFM (French Muscular Dystrophy Association), CNRS (French National Center for Scientific Research), Universite Pierre et Marie Curie, and IBM were investigating protein–protein interactions for more than 2,200 proteins whose structures are known, with particular focus on those proteins that play a role in neuromuscular diseases. Phase 2 was launched on May 12, 2009, and completed on September 26, 2012. The database of information produced will help researchers design molecules to inhibit or enhance binding of particular macromolecules, hopefully leading to better treatments for muscular dystrophy and other neuromuscular diseases. Phase 2 of the Help Cure Muscular Dystrophy project began once the results from the first phase had been analyzed. Phase 2 ran on the BOINC platform.
=== Discovering Dengue Drugs – Together – Phase 2 ===
Discovering Dengue Drugs – Together – Phase 2 (launched February 17, 2010) is sponsored by The University of Texas Medical Branch (UTMB) in Galveston, Texas, United States and the University of Chicago in Illinois, USA. The mission is to identify promising drug candidates to combat the Dengue, Hepatitis C, West Nile, Yellow Fever, and other related viruses. The extensive computing power of World Community Grid will be used to complete the structure-based drug discovery calculations required to identify these drug candidates.
=== Computing for Clean Water === Computing for Clean Water (launched September 20, 2010) is sponsored by the Center for Nano and Micro Mechanics of Tsinghua University in Beijing. The project's mission is to provide deeper insight on the molecular scale into the origins of the efficient flow of water through a novel class of filter materials. This insight will in turn guide future development of low-cost and more efficient water filters. It is estimated that 1.2 billion people lack access to safe drinking water, and 2.6 billion have little or no sanitation. As a result, millions of people die annually – an estimated 3,900 children a day due to a lack of clean water. On April 25, 2014, the project scientists released an update stating that they had exciting results to report when the paper is submitted and that the project on WCG was finished.
=== Drug Search for Leishmaniasis === Drug Search for Leishmaniasis (launched September 7, 2011) is spearheaded by the University of Antioquia in Medellín, Colombia, with assistance from researchers at the University of Texas Medical Branch in Galveston, Texas. The mission is to identify potential molecule candidates that could possibly be developed into treatments for Leishmaniasis. The extensive computing power of World Community Grid will be used to perform computer simulations of the interactions between millions of chemical compounds and certain target proteins. This will help find the most promising compounds that may lead to effective treatments for the disease.
=== GO Fight Against Malaria Project === The mission of the GO Fight Against Malaria project (launched November 16, 2011) is to discover promising drug candidates that could be developed into new drugs that cure drug resistant forms of malaria. The computing power of World Community Grid will be used to perform computer simulations of the interactions between millions of chemical compounds and certain target proteins, to predict their ability to eliminate malaria. The best compounds will be tested by scientists at The Scripps Research Institute in La Jolla, California, U.S.A. and further developed into possible treatments for the disease.
=== Say No to Schistosoma === Say No to Schistosoma (launched February 22, 2012) was the 20th research project to be launched on World Community Grid. The researchers at Infórium University in Belo Horizonte and FIOCRUZ-Minas, Brazil, ran this project on World Community Grid to perform computer simulations of the interactions between millions of chemical compounds and certain target proteins in the hope of finding effective treatments for schistosomiasis. As of April 2015, subsequent analysis had been performed, and three of the most promising candidate substances had been identified for in-vitro testing.
=== Computing for Sustainable Water === Computing for Sustainable Water was the 21st research project to be launched on World Community Grid. The researchers at the University of Virginia were running this project on World Community Grid to study the effects of human activity on a large watershed and gain deeper insights into what actions can support the restoration, health and sustainability of this important water resource. The project was launched on April 17, 2012, and completed on October 17, 2012.
=== Uncovering Genome Mysteries === The Uncovering Genome Mysteries project launched on October 16, 2014, and is a joint collaboration between Australian and Brazilian scientists. The project aims to examine close to 200 million genes from many life forms and compare them with known genes in order to find out what their function is. The results could have an effect in fields such as medicine and environmental research.
=== Outsmart Ebola Together === Outsmart Ebola Together was a collaboration with the Scripps Research Institute to help find chemical compounds to fight Ebola virus disease. It was launched on 3 December 2014. The aim is to block crucial steps in the life cycle of the virus, by finding drugs with high binding affinity with certain of its proteins. There are two targets: a surface protein used by the virus to infect human cells, and "transformer" proteins which change shape to carry out different functions. The project officially completed December 6, 2018.
=== OpenZika === OpenZika was launched on May 18, 2016, to help combat the Zika virus. The project targets proteins that are believed to be used by the Zika virus to survive and spread in the body, based on known results from similar diseases like dengue fever and yellow fever. These results will help researchers develop an anti-Zika drug. The project officially completed December 13, 2019.
=== FightAIDS@Home ===