kb/data/en.wikipedia.org/wiki/Hyperkatifeia-0.md

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Hyperkatifeia 1/1 https://en.wikipedia.org/wiki/Hyperkatifeia reference science, encyclopedia 2026-05-05T07:29:26.364618+00:00 kb-cron

Hyperkatifeia is defined as hypersensitivity to emotional distress in the context of opioid abuse. Hyperkatifeia and opioid-induced hyperalgesia can be seen with long-term use of illicit street opioids e.g. heroin, and prescription opioids e.g. hydrocodone and oxycodone during withdrawal.

== References ==