kb/data/en.wikipedia.org/wiki/Biotrauma-0.md

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---
title: "Biotrauma"
chunk: 1/1
source: "https://en.wikipedia.org/wiki/Biotrauma"
category: "reference"
tags: "science, encyclopedia"
date_saved: "2026-05-05T07:26:36.815898+00:00"
instance: "kb-cron"
---
Although the term has occasionally been used in other ways, in medical literature biotrauma is usually defined as a severe inflammatory response produced in the lungs of patients who breathe by means of a mechanical ventilator for a long period of time. The term was coined in a 1998 paper by L. N. Tremblay and A. S. Slutsky, titled Ventilator-induced injury: from barotrauma to biotrauma. The message of that paper was that barotrauma caused by pressure differentials is only one of several types of lung damage that a ventilator can produce.
== References ==