kb/data/en.wikipedia.org/wiki/Andrew_Huxley-2.md

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Andrew Huxley 3/4 https://en.wikipedia.org/wiki/Andrew_Huxley reference science, encyclopedia 2026-05-05T16:53:41.449927+00:00 kb-cron

Quite separately, he developed the mathematical equations for the operation of myosin "cross-bridges" that generate the sliding forces between actin and myosin filaments, which cause the contraction of skeletal muscles. These equations presented an entirely new paradigm for understanding muscle contraction, which has been extended to provide understanding of almost all of the movements produced by cells above the level of bacteria. Together with the Swiss physiologist Robert Stämpfli, he evidenced the existence of saltatory conduction in myelinated nerve fibres.