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| title | chunk | source | category | tags | date_saved | instance |
|---|---|---|---|---|---|---|
| Adherence (medicine) | 5/5 | https://en.wikipedia.org/wiki/Adherence_(medicine) | reference | science, encyclopedia | 2026-05-05T07:25:48.247796+00:00 | kb-cron |
Diabetes non-compliance is 98% in US and the principal cause of complications related to diabetes including nerve damage and kidney failure. Among patients with Type 2 Diabetes, adherence was found in less than one third of those prescribed sulphonylureas and/or metformin. Patients taking both drugs achieve only 13% adherence. Other aspects that drive medicine adherence rates is the idea of perceived self-efficacy and risk assessment in managing diabetes symptoms and decision making surrounding rigorous medication regiments. Perceived control and self-efficacy not only significantly correlate with each other, but also with diabetes distress psychological symptoms and have been directly related to better medication adherence outcomes. Various external factors also impact diabetic patients' self-management behaviors including health-related knowledge/beliefs, problem-solving skills, and self-regulatory skills, which all impact perceived control over diabetic symptoms. Additionally, it is crucial to understand the decision-making processes that drive diabetics in their choices surrounding risks of not adhering to their medication. While patient decision aids (PtDAs), sets of tools used to help individuals engage with their clinicians in making decisions about their healthcare options, have been useful in decreasing decisional conflict, improving transfer of diabetes treatment knowledge, and achieving greater risk perception for disease complications, their efficacy in medication adherence has been less substantial. Therefore, the risk perception and decision-making processes surrounding diabetes medication adherence are multi-faceted and complex with socioeconomic implications as well. For example, immigrant health disparities in diabetic outcomes have been associated with a lower risk perception amongst foreign-born adults in the United States compared to their native-born counterparts, which leads to fewer protective lifestyle and treatment changes crucial for combatting diabetes. Additionally, variations in patients' perceptions of time (i.e. taking rigorous, costly medication in the present for abstract beneficial future outcomes can conflict with patients' preferences for immediate versus delayed gratification) may also present severe consequences for adherence as diabetes medication often requires systematic, routine administration.
=== Hypertension === Hypertension non-compliance (93% in US, 70% in UK) is the main cause of uncontrolled hypertension-associated heart attack and stroke. In 1975, only about 50% took at least 80% of their prescribed anti-hypertensive medications. As a result of poor compliance, 75% of patients with a diagnosis of hypertension do not achieve optimum blood-pressure control.
=== Mental illness === A 2003 review found that 41–59% of patients prescribed antipsychotics took the medication prescribed to them infrequently or not at all. Sometimes non-adherence is due to lack of insight, but psychotic disorders can be episodic and antipsychotics are then use prophylactically to reduce the likelihood of relapse rather than treat symptoms and in some cases individuals will have no further episodes despite not using antipsychotics. A 2006 review investigated the effects of compliance therapy for schizophrenia: and found no clear evidence to suggest that compliance therapy was beneficial for people with schizophrenia and related syndromes.
=== Rheumatoid arthritis === A longitudinal study has shown that adherence with treatment about 60%. The predictors of adherence were found to be more of psychological, communication and logistic nature rather than sociodemographic or clinical factors. The following factors were identified as independent predictors of adherence:
the type of treatment prescribed agreement on treatment having received information on treatment adaptation clinician perception of patient trust
== See also == Drug withdrawal Patient participation
== References ==
== External links == Adherence to long-term therapies, a report from the World Health Organization Technology report on NFC enabled smart medication packages