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Neurolaw 2/5 https://en.wikipedia.org/wiki/Neurolaw reference science, encyclopedia 2026-05-05T04:27:29.062328+00:00 kb-cron

=== Insanity defense === The tendency of the United States criminal justice system has been to limit the degree to which one can claim innocence based on mental illness. During the middle of the 20th century many courts, through the Durham Rules and the American Law Institute Model Penal Code, regarded impaired volition as legitimate grounds for the insanity defense. However, when John Hinckley was acquitted due to insanity in 1982, a reversal of this opinion occurred, which spurred a narrowing definition of mental illness. Insanity decisions became increasingly based on the MNaghten Rules, which asserted that unless one was able to prove that a mental illness kept him or her from knowing that their actions were wrong, or knowing the disposition of the criminal act, one would not be able to be tried as criminally insane. Contemporary research conducted on the prefrontal cortex has criticized this standpoint because it considers impaired volition as a factor. Many researchers and courts are beginning to consider "irresistible impulse" as legitimate grounds for mental illness. One of the factors neurosciences have added to the insanity defense is the claim that the brain “made someone do it.” In these cases, the argument is based on the notion that individuals' decisions are made for them, before they are able to consciously realize what they are doing. Further research on control and inhibition mechanisms will allow for further modifications to the insanity defense. Impaired functioning of the PFC is evidence that a prime factor in mental illness is disrupted volition. Many experiments using fMRI show that one of the functions of the PFC is to bias a person towards taking the more difficult action. This action is representative of a long-term reward, and it is competing with an action that will lead to immediate satisfaction. It is responsible for moral reasoning, including regret. Individual variations that impair the PFC are extremely detrimental to the decision-making process and give an individual a greater likelihood in a committing a crime he or she would have otherwise not committed.

=== Brain death === Injuries or illnesses that lead to a persistent vegetative state have come to the forefront of many ethical, legal, and scientific issues regarding brain death. From the exterior, it is a difficult to know when a patient is beyond hope for recovery, as well as to decide who has the right to end life support. Research initiatives in cognition have helped to develop an understanding of the vegetative state. Research has shown that although a person can be awake and conscious, he or she may not show any signs of awareness or recognition to external stimulation. In 2005, research was conducted on a 23-year-old female who suffered traumatic brain injury from an automobile accident. The woman was declared to be in a vegetative state; after five months she continued to be unresponsive, but brain pattern measurements indicated normal sleep and wake cycles. Using fMRI technology, researchers concluded that she was able to understand external stimuli via activity in specific regions of the brain. Particularly, she exhibited increased activity in the middle and superior temporal gyri similar to the way that a healthy individual would. This positive response revealed potential for medical imaging to be used to understand the implications of brain death, and to help answer legal, scientific, and ethical questions pertaining to individuals in vegetative states.

== Nootropics == Neurolaw also encompasses ethical questions regarding nootropics, or mind-enhancing drugs. Current research suggests that the future may hold powerful medications that can specifically target and alter brain function by bypassing the blood brain barrier. The potential to significantly improve one's concentration, memory, or cognition through drug-use has raised numerous questions on the legality of these substances, and their appropriateness in everyday life. Analogous to the controversy over the use of anabolic steroids in professional sports, many high schools and universities are wary of students eventually using nootropics to artificially boost academic performance. Some of the questions raised regarding the use of nootropics include:

How will these enhancers affect performance gaps between family income classes? Will it become necessary to use an enhancing drug simply to remain competitive in society? How does society distinguish between what is an acceptable substance (e.g., caffeine) and an unacceptable substance to alter one's mind? Do people have the right to experiment with substances to modify their own cognition? Scientists and ethicists have attempted to answer these questions while analyzing the overall effect on society. For example, it is largely accepted that mind-enhancing drugs are acceptable for use on patients diagnosed with cognitive disorders, as in a case of prescribing Adderall to children and adults with ADHD. However, Adderall and Ritalin have also become popular black-market drugs, most notably on college campuses. Students often use them to maintain focus when struggling to complete large amounts of schoolwork, and often become dependent on the effects produced. It is ethically debatable whether individuals who do not need nootropics should use them, and mostly unknown how continued usage could impact the brain chemistry of someone who is using nootropics for nonprescriptive reasons.

== Current research == Neurolaw advancements depend on state-of-the-art medical technology and grant-funded research. Among the most prominent technologies and disciplines used in neurolaw research are functional magnetic resonance imaging (fMRI), positron emission tomography (PET scan), magnetic resonance imaging (MRI), and epigenetics.