--- title: "Hyperkatifeia" chunk: 1/1 source: "https://en.wikipedia.org/wiki/Hyperkatifeia" category: "reference" tags: "science, encyclopedia" date_saved: "2026-05-05T07:29:26.364618+00:00" instance: "kb-cron" --- Hyperkatifeia is defined as hypersensitivity to emotional distress in the context of opioid abuse. Hyperkatifeia and opioid-induced hyperalgesia can be seen with long-term use of illicit street opioids e.g. heroin, and prescription opioids e.g. hydrocodone and oxycodone during withdrawal. == References ==