--- title: "Biotrauma" chunk: 1/1 source: "https://en.wikipedia.org/wiki/Biotrauma" category: "reference" tags: "science, encyclopedia" date_saved: "2026-05-05T07:26:36.815898+00:00" instance: "kb-cron" --- Although the term has occasionally been used in other ways, in medical literature biotrauma is usually defined as a severe inflammatory response produced in the lungs of patients who breathe by means of a mechanical ventilator for a long period of time. The term was coined in a 1998 paper by L. N. Tremblay and A. S. Slutsky, titled Ventilator-induced injury: from barotrauma to biotrauma. The message of that paper was that barotrauma caused by pressure differentials is only one of several types of lung damage that a ventilator can produce. == References ==