--- title: "Sim4" chunk: 1/1 source: "https://en.wikipedia.org/wiki/Sim4" category: "reference" tags: "science, encyclopedia" date_saved: "2026-05-05T12:17:37.931979+00:00" instance: "kb-cron" --- Sim4 is a nucleotide sequence alignment program akin to BLAST but specifically tailored to DNA to cDNA/EST (Expressed Sequence Tag) alignment (as opposed to DNA–DNA or protein–protein alignment). It was written by Florea et al. == External links == A Computer Program for Aligning a cDNA Sequence with a Genomic DNA Sequence Download