---
title: "Scientific research on the International Space Station"
chunk: 3/5
source: "https://en.wikipedia.org/wiki/Scientific_research_on_the_International_Space_Station"
category: "reference"
tags: "science, encyclopedia"
date_saved: "2026-05-05T03:30:21.358987+00:00"
instance: "kb-cron"
---

==== Cardiovascular and pulmonary systems ====
Cardiovascular and Cerebrovascular Control on Return from ISS (CCISS)
Cardiac Atrophy and Diastolic Dysfunction During and After Long Duration Spaceflight: Functional Consequences for Orthostatic Intolerance, Exercise Capability and Risk for Cardiac Arrhythmias (Integrated_Cardiovascular)
Test of Midodrine as a Countermeasure Against Post-flight Orthostatic Hypotension - Long (Midodrine-Long)
Test of Midodrine as a Countermeasure Against Post-flight Orthostatic Hypotension - Short Duration Biological Investigation (Midodrine-SDBI)
The Effects of EVA and Long-Term Exposure to Microgravity on Pulmonary Function (PuFF)
Evaluation of Maximal Oxygen Uptake and Submaximal Estimates of VO2max Before, During, and After Long Duration International Space Station Missions (VO2max)
Effect of Microgravity on the Peripheral Subcutaneous Veno-Arteriolar Reflex in Humans (Xenon1)

==== Crew healthcare systems ====
IntraVenous Fluid GENeration for Exploration Missions (IVGEN)
Stability of Pharmacotherapeutic and Nutritional Compounds (Stability)

==== Human behaviour and performance ====
Bodies In the Space Environment was an experiment run from 2009 to 2010 studying how people perceive relative direction in space.
Crewmember and Crew-Ground Interaction During International Space Station Missions (Interactions)
Behavioral Issues Associated with Isolation and Confinement: Review and Analysis of ISS Crew Journals (Journals)
Sleep-Wake Actigraphy and Light Exposure During Spaceflight-Long (Sleep-Long)
Sleep-Wake Actigraphy and Light Exposure During Spaceflight-Short (Sleep-Short)
Human Factors Assessment of Vibration Effects on Visual Performance During Launch (Visual_Performance)

==== Immune system ====
Differentiation of Bone Marrow Macrophages in Space (BONEMAC)
Cell Culture Module - Immune Response of Human Monocytes in Microgravity (CCM-Immune_Response)
Cell Culture Module - Effect of Microgravity on Wound Repair: In Vitro Model of New Blood Vessel Development (CCM-Wound_Repair)
Space Flight Induced Reactivation of Latent Epstein-Barr Virus (Epstein-Barr)
Validation of Procedures for Monitoring Crewmember Immune Function (Integrated_Immune)
Incidence of Latent Virus Shedding During Space Flight (Latent_Virus)

==== Integrated physiology ====
Advanced Diagnostic Ultrasound in Microgravity (ADUM)
Nutritional Status Assessment (Nutrition)
Dietary Intake Can Predict and Protect Against Changes in Bone Metabolism during Spaceflight and Recovery (Pro_K)
National Aeronautics and Space Administration Biological Specimen Repository (Repository)

==== Neurological and vestibular systems ====
ELaboratore Immagini TElevisive - Space 2 (ELITE-S2)
Promoting Sensorimotor Response Generalizability: A Countermeasure to Mitigate Locomotor Dysfunction After Long-Duration Space Flight (Mobility)
Bioavailability and Performance Effects of Promethazine During Space Flight (PMZ)

==== Radiation ====
Anomalous Long Term Effects in Astronauts' Central Nervous System (ALTEA)
Anomalous Long Term Effects in Astronauts' Central Nervous System - Shield (ALTEA-Shield)
Bonner Ball Neutron Detector (BBND)
Chromosomal Aberrations in Blood Lymphocytes of Astronauts (Chromosome)
Dosimetric Mapping (DOSMAP)
A Study of Radiation Doses Experienced by Astronauts in EVA (EVARM)
Organ Dose Measurement Using the Phantom Torso (Torso)
Mental Representation of Spatial Cues During Space Flight (3D-Space)

==== Other experiments ====
Long Term Microgravity: A Model for Investigating Mechanisms of Heart Disease with New Portable Equipment (Card)
Cytogenetic Effects of Ionizing Radiation in Peripheral Lymphocytes of ISS Crewmembers (Chromosome-2)
Astronaut's Energy Requirements for Long-Term Space Flight (Energy)
Neuroendocrine and Immune Responses in Humans During and After Long Term Stay at ISS (Immuno)
Motion Perception: Vestibular Adaptation to G-Transitions (MOP)
Study of Low Back Pain in Crewmembers During Space Flight (Mus)
Otolith Assessment During Postflight Re-adaptation (Otolith)
Perceptual Motor Deficits in Space (PMDIS)
Psychomotor Vigilance Self Test on the International Space Station (Reaction_Self_Test)
Study of Microbial Communities Exposed to Weightlessness (Sample)
SOdium LOading in Microgravity (SOLO)
Validation of Centrifugation as a Countermeasure for Otolith Deconditioning During Spaceflight (Spin)
Test of Reaction and Adaptation Capabilities (TRAC)
Ambiguous Tilt and Translation Motion Cues After Space Flight (Zag)

=== Biology and biotechnology ===

==== Animal biology ====
Fungal Pathogenesis, Tumorigenesis, and Effects of
Host Immunity in Space (FIT)
Mice Drawer System (MDS)
Rodent Research Hardware System

==== Cellular biology and biotechnology ====
Avian Development Facility - Development and Function of the Avian Otolith System in Normal Altered Gravity Environments (ADF-Otolith)
Avian Development Facility - Skeletal Development in embryonic Quail (ADF-Skeletal)
Cellular Biotechnology Operations Support Systems: Human Renal Cortical Cell Differentiation and Hormone Production (CBOSS-01-02-Renal)
Cellular Biotechnology Operations Support Systems: Use of NASA Bioreactor to Study Cell Cycle Regulation: Mechanisms of Colon Carcinoma Metastasis in Microgravity (CBOSS-01-Colon)
Cellular Biotechnology Operations Support Systems: Evaluation of Ovarian Tumor Cell Growth and Gene Expression (CBOSS-01-Ovarian)
Cellular Biotechnology Operations Support Systems: PC12 Pheochromocytoma Cells - A Proven Model System for Optimizing 3-D Cell Culture Biotechnology in Space (CBOSS-01-PC12)
Cellular Biotechnology Operations Support Systems: Production of Recombinant Human Erythropoietin by Mammalian Cells (CBOSS-02-Erythropoietin)
Cellular Biotechnology Operations Support Systems: The Effect of Microgravity on the Immune Function of Human Lymphoid Tissue (CBOSS-02-HLT)
Cellular Biotechnology Operations Support Systems: Fluid Dynamics Investigation (CBOSS-FDI)
Commercial Generic Bioprocessing Apparatus -
Antibiotic Production in Space (CGBA-APS)
Commercial Generic Bioprocessing Apparatus - Kidney Cell Gene Expression (CGBA-KCGE)
Commercial Generic Bioprocessing Apparatus -
Synaptogenesis in Microgravity (CGBA-SM)
Microencapsulation Electrostatic Processing System
(MEPS)
StelSys Liver Cell Function Research (StelSys)
Gene, Immune and Cellular Responses to Single and Combined Space Flight Conditions - A (TripleLux-A)
Gene, Immune and Cellular Responses to Single and Combined Space Flight Conditions - B (TripleLux-B)

==== Microbiology ====
In August 2020, scientists reported that bacteria from Earth, particularly Deinococcus radiodurans bacteria, which is highly resistant to environmental hazards, were found to survive for three years in outer space, based on studies conducted on the International Space Station. These findings support the notion of panspermia, the hypothesis that life exists throughout the Universe, distributed in various ways, including space dust, meteoroids, asteroids, comets, planetoids or contaminated spacecraft.

Microbial Drug Resistance Virulence (MDRV)
Effect of Spaceflight on Microbial Gene Expression and Virulence (Microbe)
National Laboratory Pathfinder - Cells (NLP-Cells)
National Laboratory Pathfinder - Vaccine - 1A (NLP-Vaccine-1A)
National Laboratory Pathfinder - Vaccine - 1B (NLP-Vaccine-1B)
National Lab Pathfinder - Vaccine - 1C (NLP-Vaccine-1C)
National Lab Pathfinder - Vaccine - 2 (NLP-Vaccine-2)
National Lab Pathfinder - Vaccine - 3 (NLP-Vaccine-3)
National Lab Pathfinder - Vaccine - 4 (NLP-Vaccine-4)
National Lab Pathfinder - Vaccine - 5 (NLP-Vaccine-5)
Passive Observatories for Experimental Microbial Systems (POEMS)
Streptococcus pneumoniae Expression of Genes in Space (SPEGIS)
Surface, Water and Air Biocharacterization - A Comprehensive Characterization of Microorganisms and Allergens in Spacecraft Environment (SWAB)
Yeast-Group Activation Packs (Yeast-GAP)